How can I set a default LAYOUT for my libraries (X6)

I use 3 libraries that open automatically. One opens the way I want: Groups panel is OFF, Reference panel is Bottom. The other two open the way I do NOT want: Groups are ON and Reference panel is at the Right. Is there a way to avoid changing the layout manually for these 2 libraries, every time I open Endnote?

Did you try closing each of them individually with the settings as you like, and then try opening endnote again? 

Yes, I’ve don that multiple times. It seems odd that thre 3 libraries come up with different layouts.

hmmm, dare I say, Tech Support!