Howto install Endnote x2 on a server and make a client to connect to it ?

You cannot install EndNote X2 on a server and then have workstation machines run EndNote from the server.  You need to install EndNote on each on the workstations.

If you share a library on the network you must set the sharing permissions to Read-Only for all users.  If the library is going to be accessed by multiple users at the same time it has to be Read-Only.