How to get hyperlinked DOIs?

I wonder if this topic can be revisted. The need to to global find and replace after the fact in MS Word to remove the extra DOI<space> is not a good solution. 

The endnote database citiation is of the format 

DOI: 10.1021/ja00049a083

where we need the output style to end up

https//doi.org/10.1021/ja00049a083

not 

https//doi.org/DOI: 10.1021/ja00049a083

or worse 

https//doi.org/ DOI: 10.1021/ja00049a083

Is there an option is the output style format edtor to look for the string <space>DOI<space> and remove it from the output ?

There are few threads about this and none have the solution by the look.