What is the difference between “reference manager” and “Endnote”?

What is the difference between “reference manager” and “Endnote”?

Many thanks for the help

Best

Jamal

Here’s Thomson Reuter’s Comparison table: http://thomsonreuters.com/products_services/science/science_products/a-z/reference_manager/#tab2

For me, some of the biggest differences between are Endnote has Endnote Web, and Reference Manager is easiest for multi-user/team access (compared to Endnote Desktop at least). Also Endnote is updated annually; RefMan every 4-5 years. Because of this, Endnote has some nice new features. 

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many thanks for the answer.

appreciated

jamal