EndNote & The 'Cloud' | Options? Dangers? Recommendations?

Hello;

My EndNote library is precious to me :wink:  And since I don’t want to lose anything, I’ve been kinda manic about backing up.

But I’m curious if the scenario I describe below is advisable or otherwise not recommended.

I’ve mapped a drive to a could storage drive.  Can I use that location for my EndNote library?  It seems to run fine from the virtual drive, but I don’t know what risks of corrupting my database I may incur by doing so.

Another option is that I can store the files locally, and they’d be synced to the cloud drive. 

Thanks in advance.