Within the last couple of weeks, Endnote stopped communicating with Word. Another colleague of has the same problem now too. I had to reinstall Word, do all of the updates BUT did not do 5/18/08 update(!!!) then reinstall Endnote.
Is the 5/18/08 Microsoft update the issue? My hypothesis is that it may be affecting the function of Visual Basic Editor in Word which is needed for Endnote to work properly.